DNA bands

It was a world first. Insiders knew that the condensin protein plays a role in the folding and fixing of DNA strands, but no one had ever seen how this occurred. Since Jorine Eeftens and Allard Katan from the Cees Dekker Lab (Bionanoscience) published on the subject, that has all changed. In their film and in the cover article in ‘Cell Reports’ (1 March 2016), they demonstrate that condensin is a much more active and more flexible molecule than first thought. ‘Until recently, people saw it as a kind of hairpin with two positions: open and closed,’ explains Eeftens. ‘But a better comparison would be an elastic band.’ It was the first time that the protein was filmed in action with an atomic force microscope (AFM). delta.tudelft.nl/31308

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